Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands

BACKGROUND: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role in tumor development, CpG island methylation contributes to the acquisition of resistance to chemotherapy. Differential...

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Detalhes bibliográficos
Main Authors: Dai, Wei, Teodoridis, Jens M, Graham, Janet, Zeller, Constanze, Huang, Tim HM, Yan, Pearlly, Vass, J Keith, Brown, Robert, Paul, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529322/
https://ncbi.nlm.nih.gov/pubmed/18691414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-337
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