Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands

BACKGROUND: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role in tumor development, CpG island methylation contributes to the acquisition of resistance to chemotherapy. Differential...

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Bibliografske podrobnosti
Main Authors: Dai, Wei, Teodoridis, Jens M, Graham, Janet, Zeller, Constanze, Huang, Tim HM, Yan, Pearlly, Vass, J Keith, Brown, Robert, Paul, Jim
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529322/
https://ncbi.nlm.nih.gov/pubmed/18691414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-337
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