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Systematic CpG Islands Methylation Profiling of Genes in the Wnt Pathway in Epithelial Ovarian Cancer Identifies Biomarkers of Progression-Free Survival

PURPOSE: Wnt pathways control key biological processes that potentially impact on tumour progression and patient survival. We aimed to evaluate DNA methylation at promoter CpG islands (CGIs) of Wnt pathway genes in ovarian tumours at presentation and identify biomarkers of patient progression-free s...

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Detalhes bibliográficos
Main Authors: Dai, Wei, Teodoridis, Jens M., Zeller, Constanze, Graham, Janet, Hersey, Jenny, Flanagan, James M., Stronach, Euan, Millan, David W., Siddiqui, Nadeem, Paul, Jim, Brown, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431504/
https://ncbi.nlm.nih.gov/pubmed/21459799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3021
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