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Modeling methylation dynamics with simultaneous changes in CpG islands

BACKGROUND: In vertebrate genomes, CpG sites can be clustered into CpG islands, and the amount of methylation in a CpG island can change due to gene regulation processes. Thus, single regulatory events can simultaneously change the methylation states of many CpG sites within a CpG island. This shoul...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Grosser, Konrad, Metzler, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079395/
https://ncbi.nlm.nih.gov/pubmed/32183713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3438-5
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