High-throughput methylation profiling by MCA coupled to CpG island microarray

An abnormal pattern of DNA methylation occurs at specific genes in almost all neoplasms. The lack of high-throughput methods with high specificity and sensitivity to detect changes in DNA methylation has limited its application for clinical profiling. Here we overcome this limitation and present an...

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Bibliografiska uppgifter
Huvudupphovsmän: Estécio, Marcos R.H., Yan, Pearlly S., Ibrahim, Ashraf E.K., Tellez, Carmen S., Shen, Lanlan, Huang, Tim H.-M., Issa, Jean-Pierre J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2007
Ämnen:
Methods
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987348/
https://ncbi.nlm.nih.gov/pubmed/17785535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6417007
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