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CCL2 Protects Prostate Cancer PC3 Cells from Autophagic Death via Phosphatidylinositol 3-Kinase/AKT-dependent Survivin Up-regulation

Resistance to cell death is a hallmark of cancer. Autophagy is a survival mechanism activated in response to nutrient deprivation; however, excessive autophagy will ultimately induce cell death in a nonapoptotic manner. The present study demonstrates that CCL2 protects prostate cancer PC3 cells from...

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Detalhes bibliográficos
Main Authors: Roca, Hernan, Varsos, Zachary, Pienta, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529129/
https://ncbi.nlm.nih.gov/pubmed/18611860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801073200
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