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CCL2 Protects Prostate Cancer PC3 Cells from Autophagic Death via Phosphatidylinositol 3-Kinase/AKT-dependent Survivin Up-regulation

Resistance to cell death is a hallmark of cancer. Autophagy is a survival mechanism activated in response to nutrient deprivation; however, excessive autophagy will ultimately induce cell death in a nonapoptotic manner. The present study demonstrates that CCL2 protects prostate cancer PC3 cells from...

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Hlavní autoři: Roca, Hernan, Varsos, Zachary, Pienta, Kenneth J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529129/
https://ncbi.nlm.nih.gov/pubmed/18611860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801073200
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