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IL-4 induces proliferation in prostate cancer PC3 cells under nutrient-depletion stress through the activation of the JNK-pathway and survivin upregulation

Interleukin (IL)-4 plays a critical role in the regulation of immune responses and has been detected at high levels in the tumor microenvironment of cancer patients where it correlates with the grade of malignancy. The direct effect of IL-4 on cancer cells has been associated with increased cell sur...

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Detalhes bibliográficos
Main Authors: Roca, Hernan, Craig, Matthew J., Ying, Chi, Varsos, Zachary S., Czarnieski, Paul, Alva, Ajjai S., Hernandez, James, Fuller, David, Daignault, Stephanie, Healy, Patrick N., Pienta, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337359/
https://ncbi.nlm.nih.gov/pubmed/22174091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24025
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