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IL-4 induces proliferation in prostate cancer PC3 cells under nutrient-depletion stress through the activation of the JNK-pathway and survivin upregulation

Interleukin (IL)-4 plays a critical role in the regulation of immune responses and has been detected at high levels in the tumor microenvironment of cancer patients where it correlates with the grade of malignancy. The direct effect of IL-4 on cancer cells has been associated with increased cell sur...

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Détails bibliographiques
Auteurs principaux: Roca, Hernan, Craig, Matthew J., Ying, Chi, Varsos, Zachary S., Czarnieski, Paul, Alva, Ajjai S., Hernandez, James, Fuller, David, Daignault, Stephanie, Healy, Patrick N., Pienta, Kenneth J.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337359/
https://ncbi.nlm.nih.gov/pubmed/22174091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24025
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