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CCL2 and Interleukin-6 Promote Survival of Human CD11b(+) Peripheral Blood Mononuclear Cells and Induce M2-type Macrophage Polarization

CCL2 and interleukin (IL)-6 are among the most prevalent cytokines in the tumor microenvironment, with expression generally correlating with tumor progression and metastasis. CCL2 and IL-6 induced expression of each other in CD11b(+) cells isolated from human peripheral blood. It was demonstrated th...

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Autors principals: Roca, Hernan, Varsos, Zachary S., Sud, Sudha, Craig, Matthew J., Ying, Chi, Pienta, Kenneth J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797202/
https://ncbi.nlm.nih.gov/pubmed/19833726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.042671
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