The Chemokine CCL2 Increases Prostate Tumor Growth and Bone Metastasis through Macrophage and Osteoclast Recruitment

CC chemokine ligand 2 (CCL2, also known as monocyte chemoattractant protein-1) has been demonstrated to recruit monocytes to tumor sites. Monocytes are capable of being differentiated into tumor-associated macrophages (TAMs) and osteoclasts (OCs). TAMs have been shown to promote tumor growth in seve...

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Bibliographic Details
Main Authors: Mizutani, Kosuke, Sud, Sudha, McGregor, Natalie A, Martinovski, Gari, Rice, Brandon T, Craig, Matthew J, Varsos, Zachary S, Roca, Hernan, Pienta, Kenneth J
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767225/
https://ncbi.nlm.nih.gov/pubmed/19881959
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