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The Phosphatidylinositol 3-Kinase/Akt Cassette Regulates Purine Nucleotide Synthesis

The phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway is highly conserved throughout evolution and regulates cell size and survival and cell cycle progression. It regulates the latter by stimulating procession through G(1) and the G(1)/S phase transition. Entry into S phase requires an abun...

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Detalhes bibliográficos
Main Authors: Wang, Wei, Fridman, Alla, Blackledge, William, Connelly, Stephen, Wilson, Ian A., Pilz, Renate B., Boss, Gerry R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635033/
https://ncbi.nlm.nih.gov/pubmed/19068483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806707200
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