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Strain-induced Proliferation Requires the Phosphatidylinositol 3-Kinase/AKT/Glycogen Synthase Kinase Pathway

The intestinal epithelium is repetitively deformed by shear, peristalsis, and villous motility. Such repetitive deformation stimulates the proliferation of intestinal epithelial cells on collagen or laminin substrates via ERK, but the upstream mediators of this effect are poorly understood. We hypot...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gayer, Christopher P., Chaturvedi, Lakshmi S., Wang, Shouye, Craig, David H., Flanigan, Thomas, Basson, Marc D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629112/
https://ncbi.nlm.nih.gov/pubmed/19047055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804576200
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