Makorin-2 Is a Neurogenesis Inhibitor Downstream of Phosphatidylinositol 3-Kinase/Akt (PI3K/Akt) Signal

Makorin-2 belongs to the makorin RING zinc finger gene family, which encodes putative ribonucleoproteins. Here we cloned the Xenopus makorin-2 (mkrn2) and characterized its function in Xenopus neurogenesis. Forced overexpression of mkrn2 produced tadpoles with dorso-posterior deficiencies and small-...

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Bibliografiske detaljer
Main Authors: Yang, Pai-Hao, Cheung, William K. C., Peng, Ying, He, Ming-Liang, Wu, Guo-Qing, Xie, Dan, Jiang, Bing-Hua, Huang, Qiu-Hua, Chen, Zhu, Lin, Marie C. M., Kung, Hsiang-Fu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2417189/
https://ncbi.nlm.nih.gov/pubmed/18198183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M704768200
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