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Myotubularin Regulates Akt-dependent Survival Signaling via Phosphatidylinositol 3-Phosphate

Myotubularin is a 3-phosphoinositide phosphatase that is mutated in X-linked myotubular myopathy, a severe neonatal disorder in which skeletal muscle development and/or regeneration is impaired. In this report we provide evidence that siRNA-mediated silencing of myotubularin expression markedly inhi...

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書誌詳細
主要な著者: Razidlo, Gina L., Katafiasz, Dawn, Taylor, Gregory S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103374/
https://ncbi.nlm.nih.gov/pubmed/21478156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197749
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