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Myotubularin Regulates Akt-dependent Survival Signaling via Phosphatidylinositol 3-Phosphate
Myotubularin is a 3-phosphoinositide phosphatase that is mutated in X-linked myotubular myopathy, a severe neonatal disorder in which skeletal muscle development and/or regeneration is impaired. In this report we provide evidence that siRNA-mediated silencing of myotubularin expression markedly inhi...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103374/ https://ncbi.nlm.nih.gov/pubmed/21478156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197749 |
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