The myotubularin MTMR4 regulates phagosomal phosphatidylinositol 3-phosphate turnover and phagocytosis

Macrophage phagocytosis is required for effective clearance of invading bacteria and other microbes. Coordinated phosphoinositide signaling is critical both for phagocytic particle engulfment and subsequent phagosomal maturation to a degradative organelle. Phosphatidylinositol 3-phosphate (PtdIns(3)...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Sheffield, David A., Jepsen, Malene R., Feeney, Sandra J., Bertucci, Micka C., Sriratana, Absorn, Naughtin, Monica J., Dyson, Jennifer M., Coppel, Ross L., Mitchell, Christina A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851315/
https://ncbi.nlm.nih.gov/pubmed/31543504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009133
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