The myotubularin MTMR4 regulates phagosomal phosphatidylinositol 3-phosphate turnover and phagocytosis

Macrophage phagocytosis is required for effective clearance of invading bacteria and other microbes. Coordinated phosphoinositide signaling is critical both for phagocytic particle engulfment and subsequent phagosomal maturation to a degradative organelle. Phosphatidylinositol 3-phosphate (PtdIns(3)...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sheffield, David A., Jepsen, Malene R., Feeney, Sandra J., Bertucci, Micka C., Sriratana, Absorn, Naughtin, Monica J., Dyson, Jennifer M., Coppel, Ross L., Mitchell, Christina A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851315/
https://ncbi.nlm.nih.gov/pubmed/31543504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009133
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