Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

Epigenetic reprogramming is commonly observed in cancer, and is hypothesized to involve multiple mechanisms, including DNA methylation and Polycomb repressive complexes (PRCs). Here we devise a new experimental and analytical strategy using customized high-density tiling arrays to investigate coordi...

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Bibliografische gegevens
Hoofdauteurs: Gal-Yam, Einav Nili, Egger, Gerda, Iniguez, Leo, Holster, Heather, Einarsson, Steingrímur, Zhang, Xinmin, Lin, Joy C., Liang, Gangning, Jones, Peter A., Tanay, Amos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529074/
https://ncbi.nlm.nih.gov/pubmed/18753622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806437105
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