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Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

Epigenetic reprogramming is commonly observed in cancer, and is hypothesized to involve multiple mechanisms, including DNA methylation and Polycomb repressive complexes (PRCs). Here we devise a new experimental and analytical strategy using customized high-density tiling arrays to investigate coordi...

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מידע ביבליוגרפי
Main Authors: Gal-Yam, Einav Nili, Egger, Gerda, Iniguez, Leo, Holster, Heather, Einarsson, Steingrímur, Zhang, Xinmin, Lin, Joy C., Liang, Gangning, Jones, Peter A., Tanay, Amos
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529074/
https://ncbi.nlm.nih.gov/pubmed/18753622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806437105
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