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Hyperconserved CpG domains underlie Polycomb-binding sites
Comparative genomics of CpG dinucleotides, which are targets of DNA methyltransferases in vertebrate genomes, has been constrained by their evolutionary instability and by the effect of methylation on their mutation rates. We compared the human and chimpanzee genomes to identify DNA sequence signatu...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838490/ https://ncbi.nlm.nih.gov/pubmed/17376869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609746104 |
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