Gene silencing as a threat to the success of gene therapy

Por Bestor, Timothy H.
Publicado em 2000

Imprinting errors and developmental asymmetry.

Por Bestor, Timothy H
Publicado em 2003

Biological Functions of DNA Methyltransferase 1 Require Its Methyltransferase Activity

Por Damelin, Marc, Bestor, Timothy H.
Publicado em 2007

Cytosine methylation and mammalian development

Por Walsh, Colum P., Bestor, Timothy H.
Publicado em 1999

Reply to Wilkinson: Minor role of programmed methylation and demethylation in mammalian development

Por Bestor, Timothy H., Edwards, John R., Boulard, Mathieu
Publicado no Proc Natl Acad Sci U S A (2015)

Notes on the role of dynamic DNA methylation in mammalian development

Por Bestor, Timothy H., Edwards, John R., Boulard, Mathieu
Publicado no Proc Natl Acad Sci U S A (2015)

Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10

Por Boulard, Mathieu, Edwards, John R., Bestor, Timothy H.
Publicado no Epigenetics Chromatin (2016)

Mammalian cytosine methylation at a glance

Por Ooi, Steen K. T., O'Donnell, Anne H., Bestor, Timothy H.
Publicado em 2009

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

Por Song, Jikui, Rechkoblit, Olga, Bestor, Timothy H., Patel, Dinshaw J.
Publicado no Science (2010)

Reactivation of a silenced <it>H19</it> gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation

Por Bestor Timothy H, Tycko Benjamin, Lynch Catherine A, Walsh Colum P
Publicado em 2002-07-01

Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation

Por Lynch, Catherine A, Tycko, Benjamin, Bestor, Timothy H, Walsh, Colum P
Publicado em 2002

Hyperconserved CpG domains underlie Polycomb-binding sites

Por Tanay, Amos, O'Donnell, Anne H., Damelin, Marc, Bestor, Timothy H.
Publicado em 2007

Allele-specific demethylation at an imprinted mammalian promoter

Por Wood, Andrew J., Bourc’his, Déborah, Bestor, Timothy H., Oakey, Rebecca J.
Publicado em 2007

Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA

Por Dong, Aiping, Yoder, Jeffrey A., Zhang, Xing, Zhou, Lan, Bestor, Timothy H., Cheng, Xiaodong
Publicado em 2001

Coordinate regulation of DNA methyltransferase expression during oogenesis

Por Lucifero, Diana, La Salle, Sophie, Bourc'his, Déborah, Martel, Josée, Bestor, Timothy H, Trasler, Jacquetta M
Publicado em 2007

Large-scale structure of genomic methylation patterns

Por Rollins, Robert A., Haghighi, Fatemeh, Edwards, John R., Das, Rajdeep, Zhang, Michael Q., Ju, Jingyue, Bestor, Timothy H.
Publicado em 2006

Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L

Por La Salle, Sophie, Oakes, Christopher C, Neaga, Oana R, Bourc'his, Déborah, Bestor, Timothy H, Trasler, Jacquetta M
Publicado em 2007

Dynamic instability of genomic methylation patterns in pluripotent stem cells

Por Ooi, Steen KT, Wolf, Daniel, Hartung, Odelya, Agarwal, Suneet, Daley, George Q, Goff, Stephen P, Bestor, Timothy H
Publicado em 2010

Identification of the control region for tissue-specific imprinting of the stimulatory G protein α-subunit

Por Liu, Jie, Chen, Min, Deng, Chuxia, Bourc'his, Déborah, Nealon, Julie G., Erlichman, Beth, Bestor, Timothy H., Weinstein, Lee S.
Publicado em 2005

Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation

Por Mahadevaiah, Shantha K., Bourc'his, Déborah, de Rooij, Dirk G., Bestor, Timothy H., Turner, James M.A., Burgoyne, Paul S.
Publicado em 2008