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Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA

DNMT2 is a human protein that displays strong sequence similarities to DNA (cytosine-5)-methyltransferases (m(5)C MTases) of both prokaryotes and eukaryotes. DNMT2 contains all 10 sequence motifs that are conserved among m(5)C MTases, including the consensus S-adenosyl-l-methionine-binding motifs an...

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Bibliografske podrobnosti
Main Authors: Dong, Aiping, Yoder, Jeffrey A., Zhang, Xing, Zhou, Lan, Bestor, Timothy H., Cheng, Xiaodong
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC29660/
https://ncbi.nlm.nih.gov/pubmed/11139614
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