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Biological Functions of DNA Methyltransferase 1 Require Its Methyltransferase Activity
DNA methyltransferase 1 (DNMT1) has been reported to interact with a wide variety of factors and to contain intrinsic transcriptional repressor activity. When a conservative point mutation was introduced at the key catalytic residue, mutant DNMT1 failed to rescue any of the phenotypes of Dnmt1-null...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1900033/ https://ncbi.nlm.nih.gov/pubmed/17371843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00036-07 |
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