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Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale

Methylation of a CpG island is a faithful marker of silencing of its associated gene. Different approaches report the methylation status of a CpG island based on the determination of one or a few CpG sites by assuming the homogeneity of methylation along the element. This strategy is frequently appl...

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Autores principales: Barrera, Víctor, Peinado, Miguel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526261/
https://ncbi.nlm.nih.gov/pubmed/23066096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks928
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