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Evaluation of single CpG sites as proxies of CpG island methylation states at the genome scale
Methylation of a CpG island is a faithful marker of silencing of its associated gene. Different approaches report the methylation status of a CpG island based on the determination of one or a few CpG sites by assuming the homogeneity of methylation along the element. This strategy is frequently appl...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526261/ https://ncbi.nlm.nih.gov/pubmed/23066096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks928 |
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