Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

Epigenetic reprogramming is commonly observed in cancer, and is hypothesized to involve multiple mechanisms, including DNA methylation and Polycomb repressive complexes (PRCs). Here we devise a new experimental and analytical strategy using customized high-density tiling arrays to investigate coordi...

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Detalles Bibliográficos
Main Authors: Gal-Yam, Einav Nili, Egger, Gerda, Iniguez, Leo, Holster, Heather, Einarsson, Steingrímur, Zhang, Xinmin, Lin, Joy C., Liang, Gangning, Jones, Peter A., Tanay, Amos
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529074/
https://ncbi.nlm.nih.gov/pubmed/18753622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806437105
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