TcR-induced regulated secretion leads to surface expression of CTLA-4 in CD4(+)CD25(+) T cells

In this study we show that CD4(+) T cells develop a functional regulated secretory compartment after differentiation into effector cells, as shown by their increased expression and T-cell receptor-induced exocytosis of lysosomal and cytotoxic effector proteins. We tested the hypothesis that activati...

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Bibliografiska uppgifter
Huvudupphovsmän: Catalfamo, Marta, Tai, Xuguang, Karpova, Tatiana, McNally, James, Henkart, Pierre A
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2008
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2526261/
https://ncbi.nlm.nih.gov/pubmed/18397268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02822.x
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