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Structural basis for EGFR ligand sequestration by Argos
Members of the Epidermal Growth Factor Receptor (EGFR) or ErbB/HER family and their activating ligands are essential regulators of diverse developmental processes1,2. Inappropriate activation of these receptors is a key feature of many human cancers3, and its reversal is an important clinical goal....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2526102/ https://ncbi.nlm.nih.gov/pubmed/18500331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06978 |
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