Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

Apelin and its cognate G protein–coupled receptor APJ constitute a signaling pathway with a positive inotropic effect on cardiac function and a vasodepressor function in the systemic circulation. The apelin-APJ pathway appears to have opposing physiological roles to the renin-angiotensin system. Her...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chun, Hyung J., Ali, Ziad A., Kojima, Yoko, Kundu, Ramendra K., Sheikh, Ahmad Y., Agrawal, Rani, Zheng, Lixin, Leeper, Nicholas J., Pearl, Nathan E., Patterson, Andrew J., Anderson, Joshua P., Tsao, Philip S., Lenardo, Michael J., Ashley, Euan A., Quertermous, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2008
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525695/
https://ncbi.nlm.nih.gov/pubmed/18769630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34871
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