Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation

Apelin is a potent inodilator with recently described antiatherogenic properties. We hypothesized that apelin might also attenuate abdominal aortic aneurysm (AAA) formation by limiting disease-related vascular wall inflammation. C57BL/6 mice implanted with osmotic pumps filled with apelin or saline...

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Main Authors: Leeper, Nicholas J., Tedesco, Maureen M., Kojima, Yoko, Schultz, Geoffrey M., Kundu, Ramendra K., Ashley, Euan A., Tsao, Phillip S., Dalman, Ronald L., Quertermous, Thomas
Format: Artigo
Language:Inglês
Published: American Physiological Society 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685356/
https://ncbi.nlm.nih.gov/pubmed/19304942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01341.2008
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