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TLR4-induced IFN-γ production increases TLR2 sensitivity and drives Gram-negative sepsis in mice
Gram-negative bacterial infection is a major cause of sepsis and septic shock. An important inducer of inflammation underlying both syndromes is the cellular recognition of bacterial products through pattern recognition receptors (PRRs), including Toll-like receptors (TLRs). We identified a novel an...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525587/ https://ncbi.nlm.nih.gov/pubmed/18644971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071990 |
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