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Metabolic Signaling Drives IFN-γ
IFN-γ is a critical inflammatory cytokine that is closely regulated to cellular metabolic status and requires high rates of glycolysis. It has now been shown that a key mechanism to link these pathways is through maintenance of acetyl-CoA and epigenetic regulation of the IFNG locus.
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| Pubblicato in: | Cell Metab |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5292925/ https://ncbi.nlm.nih.gov/pubmed/27829134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.10.018 |
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