TLR9-Dependent and Independent Pathways Drive Activation of the Immune System by Propionibacterium Acnes

Propionibacterium acnes is usually a relatively harmless commensal. However, under certain, poorly understood conditions it is implicated in the etiology of specific inflammatory diseases. In mice, P. acnes exhibits strong immunomodulatory activity leading to splenomegaly, intrahepatic granuloma for...

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Hauptverfasser: Tchaptchet, Sandrine, Gumenscheimer, Marina, Kalis, Christoph, Freudenberg, Nikolaus, Hölscher, Christoph, Kirschning, Carsten J., Lamers, Marinus, Galanos, Chris, Freudenberg, Marina A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382180/
https://ncbi.nlm.nih.gov/pubmed/22745710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039155
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