TLR9-Dependent and Independent Pathways Drive Activation of the Immune System by Propionibacterium Acnes

Propionibacterium acnes is usually a relatively harmless commensal. However, under certain, poorly understood conditions it is implicated in the etiology of specific inflammatory diseases. In mice, P. acnes exhibits strong immunomodulatory activity leading to splenomegaly, intrahepatic granuloma for...

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Main Authors: Tchaptchet, Sandrine, Gumenscheimer, Marina, Kalis, Christoph, Freudenberg, Nikolaus, Hölscher, Christoph, Kirschning, Carsten J., Lamers, Marinus, Galanos, Chris, Freudenberg, Marina A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382180/
https://ncbi.nlm.nih.gov/pubmed/22745710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039155
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