Increased TLR4 Expression Aggravates Sepsis by Promoting IFN-γ Expression in CD38(−/−) Mice

Gram-negative bacterial sepsis accounts for up to 50% worldwide sepsis that causes hospital mortality. Acute kidney injury (AKI), a common complication of Gram-negative bacterial sepsis, is caused by Toll-like receptor 4 (TLR4) activation. Lipopolysaccharide (LPS) is an endotoxin in Gram-negative ba...

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Publicado en:J Immunol Res
Autores principales: Li, Qi, Wu, Chenyi, Liu, Zhenlong, Zhang, Huiqing, Du, Yuna, Liu, Yuxiang, Song, Kuangyu, Shi, Qiaofa, Li, Rong
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399547/
https://ncbi.nlm.nih.gov/pubmed/30915370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3737890
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