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Chemically synthesized human survivin does not inhibit caspase-3
Survivin is a member of the inhibitor of apoptosis protein (IAP) family that blocks cell death by inhibiting the caspase activation pathways. Overexpressed in all common human neoplasms but undetectable in most normal adult tissues, survivin confers tumor resistance to apoptosis and represents an id...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525533/ https://ncbi.nlm.nih.gov/pubmed/18539906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.036145.108 |
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