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Chemically synthesized human survivin does not inhibit caspase-3

Survivin is a member of the inhibitor of apoptosis protein (IAP) family that blocks cell death by inhibiting the caspase activation pathways. Overexpressed in all common human neoplasms but undetectable in most normal adult tissues, survivin confers tumor resistance to apoptosis and represents an id...

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Detalhes bibliográficos
Main Authors: Li, Changqing, Wu, Zhibin, Liu, Min, Pazgier, Marzena, Lu, Wuyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525533/
https://ncbi.nlm.nih.gov/pubmed/18539906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.036145.108
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