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Transition State Analysis of S. pneumoniae 5′-Methylthioadenosine Nucleosidase
Kinetic isotope effects (KIEs) and computer modeling are used to approximate the transition state of S. pneumoniae 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN). Experimental KIEs were measured and corrected for a small forward commitment factor. Intrinsic KIEs were obtained for...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2522316/ https://ncbi.nlm.nih.gov/pubmed/17298059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja065082r |
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