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Transition State Variation in Human, Bovine and Plasmodium falciparum Adenosine Deaminases

Adenosine deaminases (ADAs) from human, bovine and Plasmodium falciparum sources were analyzed by kinetic isotope effects (KIEs) and shown to have distinct but related transition states. Human adenosine deaminase (HsADA) is present in most mammalian cells and is involved in B- and T-cell development...

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Detalhes bibliográficos
Main Authors: Luo, Minkui, Singh, Vipender, Taylor, Erika A., Schramm, Vern L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2522313/
https://ncbi.nlm.nih.gov/pubmed/17536804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja072122y
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