Načítá se...
A unique class of duocarmycin and CC-1065 analogues subject to reductive activation
N-Acyl O-amino phenol derivatives of CBI-TMI and CBI-indole(2) are reported as prototypical members of a new class of reductively activated prodrugs of the duocarmycin and CC-1065 class of antitumor agents. The expectation being that hypoxic tumor environments, with their higher reducing capacity, c...
Uloženo v:
| Hlavní autoři: | , , , , , , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519901/ https://ncbi.nlm.nih.gov/pubmed/18020335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja075398e |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|