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ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair
ERCC1-XPF endonuclease is required for nucleotide excision repair (NER) of helix-distorting DNA lesions. However, mutations in ERCC1 or XPF in humans or mice cause a more severe phenotype than absence of NER, prompting a search for novel repair activities of the nuclease. In Saccharomyces cerevisiae...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519706/ https://ncbi.nlm.nih.gov/pubmed/18541667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00293-08 |
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