Association of Hepatitis C Virus Replication Complexes with Microtubules and Actin Filaments Is Dependent on the Interaction of NS3 and NS5A

The hepatitis C virus (HCV) RNA replication complex (RC), which is composed of viral nonstructural (NS) proteins and host cellular proteins, replicates the viral RNA genome in association with intracellular membranes. Two viral NS proteins, NS3 and NS5A, are essential elements of the RC. Here, by us...

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Detalhes bibliográficos
Main Authors: Lai, Chao-Kuen, Jeng, King-Song, Machida, Keigo, Lai, Michael M. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519648/
https://ncbi.nlm.nih.gov/pubmed/18562541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00398-08
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