Photosensitized Oxidative DNA Damage: From Hole Injection to Chemical Product Formation and Strand Cleavage

Oxidatively generated damage to DNA induced by a pyrenyl photosensitizer residue (Py) covalently attached to a guanine base in the DNA sequence context 5′-d(CAT[G(1)(Py)]CG(2)TCCTAC) in aerated solutions was monitored from the initial one-electron transfer, or hole injection step, to the formation o...

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Detalhes bibliográficos
Main Authors: Yun, Byeong Hwa, Lee, Young Ae, Kim, Seog K., Kuzmin, Vladimir, Kolbanovskiy, Alexander, Dedon, Peter C., Geacintov, Nicholas E., Shafirovich, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519169/
https://ncbi.nlm.nih.gov/pubmed/17616188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja066954s
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