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One-electron oxidation of a pyrenyl photosensitizer covalently attached to DNA and competition between its further oxidation and DNA hole injection
The photosensitized hole injection and guanine base damage phenomena have been investigated in the DNA sequence, 5′-d(CATG(1)(Py)CG(2)TCCTAC) with a site-specifically positioned pyrene-like (Py) benzo[a]pyrene 7,8-diol 9,10-epoxide – derived N(2)-guanine adduct (G(1)(Py)). Generation of the Py radic...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3705723/ https://ncbi.nlm.nih.gov/pubmed/20408978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-1097.2010.00719.x |
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