Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice

BACKGROUND: Prosaposin encodes, in tandem, four small acidic activator proteins (saposins) with specificities for glycosphingolipid (GSL) hydrolases in lysosomes. Extensive GSL storage occurs in various central nervous system regions in mammalian prosaposin deficiencies. RESULTS: Our hypomorphic pro...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Sun, Ying, Jia, Li, Williams, Michael T, Zamzow, Matt, Ran, Huimin, Quinn, Brian, Aronow, Bruce J, Vorhees, Charles V, Witte, David P, Grabowski, Gregory A
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2008
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518924/
https://ncbi.nlm.nih.gov/pubmed/18673548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-76
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk