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Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice
BACKGROUND: Prosaposin encodes, in tandem, four small acidic activator proteins (saposins) with specificities for glycosphingolipid (GSL) hydrolases in lysosomes. Extensive GSL storage occurs in various central nervous system regions in mammalian prosaposin deficiencies. RESULTS: Our hypomorphic pro...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518924/ https://ncbi.nlm.nih.gov/pubmed/18673548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-76 |
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