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Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice
BACKGROUND: Prosaposin encodes, in tandem, four small acidic activator proteins (saposins) with specificities for glycosphingolipid (GSL) hydrolases in lysosomes. Extensive GSL storage occurs in various central nervous system regions in mammalian prosaposin deficiencies. RESULTS: Our hypomorphic pro...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518924/ https://ncbi.nlm.nih.gov/pubmed/18673548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-76 |
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