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Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease
Th17 is a newly identified T-cell lineage that secretes proinflammatory cytokine IL-17. Th17 cells have been shown to play a critical role in mediating autoimmune diseases such as EAE, colitis, and arthritis, but their role in the pathogenesis of graft-versus-host disease (GVHD) is still unknown. He...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518909/ https://ncbi.nlm.nih.gov/pubmed/18596226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-126987 |
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