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Elimination of insulitis and augmentation of islet β cell regeneration via induction of chimerism in overtly diabetic NOD mice
Type 1 diabetes in both humans and nonobese diabetic (NOD) mice results from autoreactive T cell destruction of insulin-producing β cells. Cure of type 1 diabetes may require both reversal of autoimmunity and regeneration of β cells. Induction of chimerism via allogeneic hematopoietic cell transplan...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785362/ https://ncbi.nlm.nih.gov/pubmed/17267595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611101104 |
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