Induction of Chimerism Permits Low-Dose Islet Grafts in the Liver or Pancreas to Reverse Refractory Autoimmune Diabetes

OBJECTIVE: To test whether induction of chimerism lowers the amount of donor islets required for reversal of diabetes and renders the pancreas a suitable site for islet grafts in autoimmune diabetic mice. RESEARCH DESIGN AND METHODS: The required donor islet dose for reversal of diabetes in late-sta...

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Hlavní autoři: Zhang, Chunyan, Wang, Miao, Racine, Jeremy J., Liu, Hongjun, Lin, Chia-Lei, Nair, Indu, Lau, Joyce, Cao, Yu-An, Todorov, Ivan, Atkinson, Mark, Zeng, Defu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2010
Témata:
Immunology and Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927945/
https://ncbi.nlm.nih.gov/pubmed/20530743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0450
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