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Mesenchymal stem cells facilitate mixed hematopoietic chimerism induction and prevent onset of diabetes in NOD mice

OBJECTIVES: Allogeneic mesenchymal stem cells (MSCs) and bone marrow cells (BMCs) were co-transplanted in NOD mice following none myeloablative preconditioning and the development of chimerism, insulitis, diabetes, and graft versus host disease (GVHD) were monitored. METHODS: Eight-weeks-old female...

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Autors principals: Asari, Sadaki, Itakura, Shin, Rawson, Jeffrey, Ito, Taihei, Todorov, Ivan, Nair, Indu, Shintaku, Jonathan, Liu, Chih-Pin, Kandeel, Fouad, Mullen, Yoko
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138826/
https://ncbi.nlm.nih.gov/pubmed/21562444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e318215cdce
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