ロード中...
Ring-Closing Metathesis for the Synthesis of a Highly G-Quadruplex Selective Macrocyclic Hexaoxazole Having Enhanced Cytotoxic Potency
The synthesis of a 24-membered macrocyclic hexaoxazole via ring-closing metathesis is described. The target compound selectively stabilizes G-quadruplex DNA with no detectable stabilization of duplex DNA. An MTT cytotoxicity assay indicated that this unsaturated macrocyclic hexaoxazole exhibits sign...
保存先:
| 主要な著者: | , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518403/ https://ncbi.nlm.nih.gov/pubmed/18515097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.05.032 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|